[2-Methoxy-5-(1-methylethyl)phenyl]boronic acid

[2-Methoxy-5-(1-methylethyl)phenyl]boronic acid - Names and Identifiers

Name	5-Isopropyl-2-methoxybenzeneboronic acid
Synonyms	AKOS BRN-0316 RARECHEM AH PB 0083 5-ISOPROPYL-2-METHOXYPHENYLBORONIC ACID 2-Methoxy-5-isopropylphenylboronic acid 5-ISOPROPYL-2-METHOXYBENZENEBORONIC ACID 5-Isopropyl-2-methoxybenzeneboronic acid (5-Isopropyl-2-methoxyphenyl)boronic acid (2-methoxy-5-propan-2-ylphenyl)boronic acid [2-methoxy-5-(1-methylethyl)phenyl]boronic acid [2-Methoxy-5-(1-methylethyl)phenyl]boronic acid boronic acid, B-[2-methoxy-5-(1-methylethyl)phenyl]-
CAS	216393-63-4
InChI	InChI=1/C10H15BO3/c1-7(2)8-4-5-10(14-3)9(6-8)11(12)13/h4-7,12-13H,1-3H3

[2-Methoxy-5-(1-methylethyl)phenyl]boronic acid - Physico-chemical Properties

Molecular Formula	C10H15BO3
Molar Mass	194.04
Density	1.08±0.1 g/cm3(Predicted)
Melting Point	84-88 °C
Boling Point	350.0±52.0 °C(Predicted)
Flash Point	165.5°C
Vapor Presure	1.69E-05mmHg at 25°C
BRN	9193266
pKa	8.60±0.58(Predicted)
Storage Condition	2-8°C
Refractive Index	1.509
MDL	MFCD01318154

[2-Methoxy-5-(1-methylethyl)phenyl]boronic acid - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

[2-Methoxy-5-(1-methylethyl)phenyl]boronic acid - Introduction

acid (acid) is an organic compound with the chemical formula C11H15BO3.

Nature:
-Appearance: Colorless crystalline solid
-Melting point: About 80-85 ℃
-Solubility: Soluble in alcohol, ether organic solvent, slightly soluble in water
-Stability: relatively stable at room temperature, but avoid prolonged exposure to air and moisture

Use:
As an important organic synthesis intermediate, acid is widely used in the synthesis of pharmaceuticals, pesticides and functional materials. Specific uses include:
-As an intermediate for the synthesis of aryl boronic acids, it can be used to construct compound skeletons
-Can be used to participate in coupling reactions, such as Suzuki coupling reactions
-Can be used as a catalyst and ligand in metal-catalyzed reactions

Method:
The synthesis of Cr acid is usually obtained from the corresponding aromatic compound (5-isopropyl-2-methoxyphenol) by nucleophilic substitution reaction or oxidation reaction of borate ester.

Safety Information:
This compound is generally relatively safe under correct handling and storage conditions, but the following matters need to be noted:
-Avoid prolonged contact with skin and eyes, and avoid inhalation or ingestion
-Wear appropriate protective equipment such as glasses, lab gloves, etc.
-should be stored sealed, away from fire and oxidizing agent
-Seek immediate medical help and carry information about the compound if inadvertently touched or ingested

Last Update：2024-04-09 19:05:47